abstract |
PCT No. PCT/FR90/00591 Sec. 371 Date Apr. 14, 1992 Sec. 102(e) Date Apr. 14, 1992 PCT Filed Sep. 6, 1990 PCT Pub. No. WO91/03558 PCT Pub. Date Mar. 21, 1991Nucleic acid fragments have been obtained from the genome of mycobacteria, and applications of the nucleic acid fragments in the diagnosis of mycobacterial infections are described. More particularly, the present invention concerns an isolated polynucleotide of the formula:5'-(SEQ ID NO: 1)-(formula III)-(SEQ ID NO: 2)-3'where formula III represents a polynucleotide containing nucleotides 343-1152 of SEQ ID NO: 3. Primers and probes based on the isolated polynucleotide, DNA complementary to any of the polynucleotides, primers or probes, a method of detecting and identifying at least one species or group of mycobacteria, and a kit, box, or coordinated set for conducting the method are also described. |