| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b73bb5b611ad02b686a7967bc6ca3412 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-0023
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-0094
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0063
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L33-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L33-08 |
| filingDate |
1995-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c9660f05b3607cc7a1cf8de88323683
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3760289f749260249124cb5ef4943ca6 |
| publicationDate |
1996-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5583213-A |
| titleOfInvention |
Process to activate sulfated polysaccharides |
| abstract |
The present specification is directed to a novel process to prepare an activated sulfated polysaccharide which may then be used in subsequent reactions or processes to bind the reactive polysaccharide with a nucleophilic agent or an aminated surface. The activating process comprises the steps of initially forming a polysaccharide tetraalkylammonium salt by contacting an aqueous mixture of a sulfated polysaccharide salt with a cation exchange resin to give a polysaccharide free acid and then contacting the polysaccharide free acid with a tetraalkylammonium hydroxide to give the polysaccharide tetraalkylammonium salt, and subsequently forming an activated sulfated polysaccharide by contacting the polysaccharide tetraalkylammonium salt of step i) with a coupling reagent in an aprotic organic solvent at ambient temperatures for a period of time sufficient to form the activated sulfated polysaccharide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8409604-B2
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010272775-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE49522-E
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005156512-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9114194-B2 |
| priorityDate |
1995-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |