| abstract |
PCT No. PCT/JP92/01419 Sec. 371 Date Jul. 25, 1994 Sec. 102(e) Date Jul. 25, 1994 PCT Filed Nov. 2, 1992 PCT Pub. No. WO93/09085 PCT Pub. Date May 13, 1993Nitroxyalkylamide compounds having the formula: R1-(A)n-CONH-B'-ONO2 wherein R1 is an optionally substituted furyl, furyloxy, thienyl, thienyloxy, isoxazolyl, phenoxy, phenylthio or 1,4-dibenzodioxanyl, A is a C1-C4 alkylene group; B' is a C1-C4 alkylene group; and n is 0 or 1. The compounds of the present invention have a desirable vasodilator action for collateral vessels and an anti-anginal action, and are useful as therapeutic agents for treating angina pectoris. |