| abstract |
PCT No. PCT/US92/05199 Sec. 371 Date Apr. 22, 1994 Sec. 102(e) Date Apr. 22, 1994 PCT Filed Jun. 18, 1992 PCT Pub. No. WO92/22319 PCT Pub. Date Dec. 23, 1992The invention relates to a family of substantially pure, receptor like TGF- beta 1 binding glycoproteins. These molecules are characterized by molecular masses of 160 kd, 70-80 kd, and 30-40 kd as determined by SDS-PAGE, and the ability to bind the TGF- beta 1 molecule. This family of molecules is useful in identifying and/or quantifying TGF- beta 1 in a sample, as well as inhibiting its effect on cells. Also described are nucleic acid sequences which code for the protein monomer making up the molecules. |