| abstract |
PCT No. PCT/JP93/00566 Sec. 371 Date Oct. 27, 1994 Sec. 102(e) Date Oct. 27, 1994 PCT Filed Apr. 28, 1993 PCT Pub. No. WO93/22317 PCT Pub. Date Nov. 11, 1993A quinoline derivative represented by general formula (1), a medicinally acceptable salt thereof, and a remedy for cardiac diseases containing the same: <IMAGE> (1) [wherein ring A represents a furan, dihydrofuran or dioxolane ring, and R1 represents an aminoalkyl group]. The compound (1) has a positively inotropic effect on myocardia and an antiarrhythmic effect, and can dilate blood vessels without extremely increasing the heart rate. Therefore, a remedy for cardiac diseases containing the same as the active ingredient is remarkably useful for treating cardiac insufficiency, arrhythmia, and so forth. |