| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94b51d317764e2f4f1bbcb355b274c8b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 |
| filingDate |
1994-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70bdc21bb861ec0125441e88a7390ac8 |
| publicationDate |
1996-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5576186-A |
| titleOfInvention |
Diagnosis and monitoring of rheumatological diseases by detection of anti-EF1-α antibodies |
| abstract |
A method and assay kit are provided for diagnosing systemic lupus erythematosus by detecting a concentration of anti-EF-1 alpha antibodies that may be found within a sample of body fluid. The assay employs substantially pure EF-1 alpha antigen, which is preferably bound to a polystyrene support, and an indicator reagent for detecting and quantifying a quantity of anti-EF-1 alpha antibody that attaches to the bound antigen. The support and bound antigen are contacted with the fluid sample to allow the formation of an antigen/antibody complex between the support-bound EF-1 alpha antigen and the anti-EF-1 alpha antibody. The urine-sample assay has a sensitivity for active SLE of at least about 90%, and a specificity of about 90%. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008240878-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009175871-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007060240-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03012048-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2894031-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007060240-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004241689-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03012048-A2 |
| priorityDate |
1994-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |