| abstract |
PCT No. PCT/GB93/00009 Sec. 371 Date Sep. 1, 1994 Sec. 102(e) Date Sep. 1, 1994 PCT Filed Jan. 6, 1993 PCT Pub. No. WO93/14072 PCT Pub. Date Jul. 19, 1993Compounds of general formula I: <IMAGE> I wherein W represents imidazo [4,5-c]pyridin-1-yl, imidazo [4,5-c]pyridin-3-yl and imidazo [4,5-c]pyridin-5-yl optionally substituted with one or more -C1-C6 alkyl substituents; Z represents a) a divalent alkanediyl, alkenediyl or alkynediyl group; b) a -(CH2)qU(CH2)r- group, optionally substituted, wherein q is an integer from 0-3, r is an integer from 0-3 and U is -O- or -S-; Q represents a carbonyl, thiocarbonyl or sulphonyl group; B represents a) a -VR8 group wherein V is -C(=O)O- or -CH2O-; are antagonists of platelet activating factor (PAF). |