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publicationDate 1996-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5554602-A
titleOfInvention Labelling of hormones with rhenium and tecnetium
abstract The disclosed invention is drawn to the organometallic oestrogen complex of formula (I): <IMAGE> (I) in which A is a C1-7 alkylene radical or C2-7 alkenylene or alkynylene radical; Mx is one or more identical or different transition metals; L'y is one or more identical or different ligands complexing the metal(s) of Mx; and L is a ligand for covalently coupling Mx to A; and R is H or a C1-7 alkyl or alkoxy group which may be optionally substituted, particularly with one or more halogens. These complexes are useful for the treatment of hormone-dependent cancers. Also, when the metals of the complex Mx are radioactive isotopes suitable for imaging, the complexes are useful as imaging agents.
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