| abstract |
N,N'-disubstituted-amidines, e.g., of the formula <IMAGE> wherein R, R' and R'' are substituted or unsubstituted hydrocarbon and/or heterocyclic groups. Methods are provided for the treatment or prophylaxis of anxiety in an animal for treating psychosis, and for treating hypertension by administering an effective amount of an N,N'-disubstituted amidine which, preferably, has a high affinity for the sigma receptor. |