abstract |
The present invention relates to a cephalosporin compound represented by the following general formula (I): <IMAGE> (I) <IMAGE> its pharmaceutically acceptable non-toxic salt, physiologically hydrolyzable ester, hydrate or solvate, or isomers thereof, in which R1 represents hydrogen or an amino-protecting group, R2 and R3 can be identical or different and independently of one another represent hydrogen or a hydroxy-protecting group, or R2 and R3 together can form a cyclic diol-protecting group, R4 represents hydrogen or a carboxyl-protecting group, R5, R6 and R7 independently of one another represent hydrogen, amino or substituted amino, hydroxy, alkoxy, C1-4 alkyl, carboxyl or alkoxycarbonyl, or R5 and R6 together with the carbon atoms to which they are attached can form a C3-7 cycle, and Q represents CH or N, and to a process for preparation thereof and a pharmaceutical composition containing the compound (I) as an active ingredient. |