abstract |
PCT No. PCT/US91/09700 Sec. 371 Date Oct. 22, 1992 Sec. 102(e) Date Oct. 22, 1992 PCT Filed Dec. 23, 1991 PCT Pub. No. WO92/12242 PCT Pub. Date Jul. 23, 1992.Genetically engineered or transduced hepatocytes which express genetic material of interest introduced or incorporated into them, as well as methods of producing, transplanting and using the genetically engineered hepatocytes are disclosed. The genetic material of interest can be incorporated through the use of a vector, such as a recombinant retrovirus, which contains the genetic material of interest, or by other means. |