http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5519128-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99505f5f312672820e9f78c254c00a4d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-20 |
filingDate | 1995-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1996-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6f6047d6aa3b8fc28541819234d4f6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ebd0c80f2bf06dc1ae63cfd9f7b3122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d20d4f3a516bf00f72bb1ba59c99632b |
publicationDate | 1996-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5519128-A |
titleOfInvention | Process for the synthesis of acylated derivatives of fatty acid-transporting thiols and in particular acyl-coenzymes A and the thus obtained acyl-coenzymes A |
abstract | The invention relates to a process for the synthesis of an acylated derivative of a fatty acid-transporting thiol such as the coenzyme A. According to this process, a silylated or stannylated thiol is prepared by reacting the thiol with a silylation or stannylation reagent in order to at least partly replace the unstable hydrogens of the thiol by SiR3 or SnR3 groups with R being an alkyl or aryl group. The silylated or stannylated thiol is then reacted in an anhydrous organic medium with an activated organic acid and a deprotection reagent able to eliminate the silyl or stannyl groups. In this way it is possible to obtain acylated derivatives of the coenzyme A, in which the acyl group can have up to 30 carbon atoms with high yields. |
priorityDate | 1993-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 205.