| abstract |
<IMAGE> (I) <IMAGE> (a) A compound of formula (I) or a pharmaceutically acceptable salt, ester or amide thereof, or a pharmaceutically acceptable solvate thereof, wherein R0 represents a substituted or unsubstituted aryl group; R1 represents hydrogen or an alkyl group; R2 represents a moiety of formula (a) wherein R4 and R5 each independently represent hydrogen, alkyl, hydroxyalkyl, cycloalkyl or R4 together with R5 represents (CH2)n wherein n is 2, 3 or 4; T represents hydrogen, nitrile or a group -CO.Rs wherein Rs represents hydroxy, alkoxy or a group -NRtRu wherein Rt and Ru independently represent hydrogen, alkyl or Rt and Ru together with the nitrogen to which they are attached represent a saturated heterocyclic group; and R3 represents hydrogen, halogen, alkyl or alkoxy; a process for the preparation of such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine. |