| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e493dbb326bdb84242fbc9af833f128e |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1688 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate |
1992-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66c8df485e2814eed63283fa422d6c35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21dd4517dd39322aa6f3c1012f0d12b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a177f090677496918c7564428fdb3a47 |
| publicationDate |
1996-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5512302-A |
| titleOfInvention |
Pharmaceutical process using starch |
| abstract |
PCT No. PCT/EP92/01953 Sec. 371 Date Mar. 4, 1994 Sec. 102(e) Date Mar. 4, 1994 PCT Filed Aug. 25, 1992 PCT Pub. No. WO93/04676 PCT Pub. Date Mar. 18, 1993.A process for the preparation of a pharmaceutical composition in the form of agglomerates comprising 70-97% by weight of 2-(4-isobutylphenyl)propionic acid or a pharmaceutically acceptable salt thereof and 3-30% by weight of a starch component, said process comprising the steps of a) forming an emulsion comprising 1) 70-97% by weight of 2-(4-isobutylphenyl)propionic acid or a salt thereof 2) a solvent system 3) 3-30% by weight of the starch component 4) water and optionally 5) a surfactant b) crystallising to produce a suspension comprising crystals of 2-(4-isobutylphenyl)propionic acid or the salt thereof in intimate contact with the starch component c) agitating said suspension to form agglomerates comprising an evenly distributed mixture of 2-(4-isobutylphenyl)propionic acid or a salt thereof and the starch component d) collecting said agglomerates and optionally e) drying said agglomerates. Pharmaceutical formulations comprising 90-99.98% by weight of such a composition together with 0.02-10% of a pharmaceutically acceptable excipient are also described, which are suitable for direct compression into tablets. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011204085-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004173147-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004173146-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005203482-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005202051-A1 |
| priorityDate |
1991-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |