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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22
filingDate 1995-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_351ae60c10a7df317261871035edf74c
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publicationDate 1996-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5500370-A
titleOfInvention Thermostable ribonuclease H and genetic constructs therefore
abstract An essentially pure preparation of thermostable RNase H isolated from Thermus flavus is disclosed. In one preferable form of the invention, the RNase H is capable of biological activity after incubation at temperatures equal to or greater than 70 DEG C. for at least ten minutes. The present invention is also a method of digesting RNA polymers that are in duplex form with a DNA molecule. The method comprises exposing the duplex to the isolated thermostable RNase H. The present invention is also a genetic construct capable of expressing a thermostable RNase H.
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priorityDate 1991-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 56.