| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb78b459e21bb4fd52850a12cab27387 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F2810-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F120-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L101-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-785
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L101-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-34 |
| filingDate |
1995-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7346eaa6d936417661a1383fe268fc8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7002cd6deee92aa2df99a6b93b935c0 |
| publicationDate |
1996-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5500212-A |
| titleOfInvention |
Crosslinked anion exchange particles and method for producing the particles |
| abstract |
New bile acid sequestrant polymer compositions and a process for preparing the polymers in particulate form, preferably in spherical form, are described. The polymer particles are prepared by crosslinking an amine-containing polymer with an amount of a polyfunctional amine-reactive compound sufficient to crosslink the polymer so that it is essentially water insoluble and has bile acid sequestering efficacy greater than that of cholestyramine, preferably greater than about three times the efficacy of cholestyramine. A preferred polymerization process revolves suspension polymerization of water-soluble amine-containing monomers, such as dialkylaminoalkyl (meth)acrylate esters and dialkylaminoalkyl (meth)acrylamides, in the presence of polyfunctional amine-reactive compounds, such as substituted dihaloalkanes. Pharmaceutical compositions containing the bile acid sequestrant polymer particles and a method for lowering blood cholesterol levels using the pharmaceutical compositions are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009155201-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5679717-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7399821-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005106267-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7101960-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008057697-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5929184-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007155950-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10555969-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6129910-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005131161-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8414927-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008226741-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083748-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008057697-A2 |
| priorityDate |
1994-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |