http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5498604-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_543c6c65952993acf92ccbb172d070c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_746d8243701ae4271b74368451625bee |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-06 |
| filingDate | 1993-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1996-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a14dfadd17b06d64438086bbab1e08ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b87a4325b5b07db3da5a56f4859f5b11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbe47c05c5d171fa1ab78c9e9db02ac1 |
| publicationDate | 1996-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5498604-A |
| titleOfInvention | Lewis-type sugar chain derivative |
| abstract | PCT No. PCT/JP93/00106 Sec. 371 Date Nov. 17, 1994 Sec. 102(e) Date Nov. 17, 1994 PCT Filed Jan. 29, 1993 PCT Pub. No. WO93/15098 PCT Pub. Date Aug. 5, 1993.The object of the present invention is to provide a new SLe-type sugar chain derivative represented by the following formula (I), which is useful as a pharmaceutical and which contains moranoline: <IMAGE> (I) wherein R1 represents hydrogen, a lower alkyl, a lower alkenyl or a lower alkynyl; R2 and R3 differ from each other and represent a galactosyl, sialylgalactosyl or fucosyl group; R4 represents a hydroxyl group or an acetamido group. The present invention comprises a sugar chain derivative containing a moranoline, and having a new structure. Possessing cell adhesion inhibitory activity, the compounds of the present invention antagonizes selectin, serving well in the treatment of inflammation, inflammation-associated thrombosis, asthma and rheumatism, and in the prevention and treatment of immunological diseases and cancer. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005243055-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5700918-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5679321-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5660992-A |
| priorityDate | 1992-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 247.