| abstract |
The invention concerns the compounds of formula I us significances, in free form and, where such forms exist, in salt form. They can be prepared by various processes, e.g. by irradiation; oxidation; elimination; reduction; conversion by e.g. halogenation or acylation; deprotection of protected hydroxy groups; protection of free hydroxy groups; and separation of stereoisomeric mixtures into individual isomers. They are useful as pharmaceuticals, especially as antiinflammatory, and as antiproliferative and antiinflammatory agents. |