| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
| filingDate |
1992-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d274a7688ad98da04d2ac05211b78426
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b81f3879d75cc90fbd5137da5676dc73 |
| publicationDate |
1995-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5474766-A |
| titleOfInvention |
Methods and compositions for inhibition of hepatic clearance of tissue-type plasminogen activator |
| abstract |
Methods and compositions for inhibiting the hepatic clearance of tissue-type plasminogen activator (t-PA) in vivo by administering a t-PA-hepatic clearance-inhibiting amount of 39 kDa protein or a t-PA-hepatic clearance-inhibiting fragment thereof, or genetically or chemically modified forms of the 39 kDa protein or fragments thereof are described. Methods and compositions for treatment of thrombolytic diseases by administering t-PA and a t-PA-hepatic clearance-inhibiting effective amount of 39 kDa protein, a t-PA-hepatic clearance inhibiting fragment thereof, and genetically or chemically modified forms of the 39 kDa protein or its fragments are described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009269346-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7829537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5650391-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6794491-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005002515-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007035716-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011142763-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9062126-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006029609-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8609103-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8877714-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9879064-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011189084-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011094536-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005042227-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010183581-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009281024-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7977317-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7560431-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005026823-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7569544-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8795627-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007167365-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7700554-B2 |
| priorityDate |
1992-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |