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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-82
filingDate 1994-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1995-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7f1c86c1fb017b34af3cd4145ea9fb5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2db680ebd04a7d7278f4056bdfc17b08
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publicationDate 1995-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5470736-A
titleOfInvention Transdominant negative proto-oncogene
abstract The present invention provides polynucleotide and polypeptide sequences for a trans-repressing protein of the Fos proto-oncogene family, where the polypeptide is characterized by having a leucine zipper domain and forming a heterodimer with a Jun related protein. This heterodimer is capable of biding to an AP-1 site and suppressing transcriptional transactivation of a promoter containing the AP-1 site.
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