| abstract |
A compound of the formula: <IMAGE> wherein R1 is aryl, or a group of the formula: <IMAGE> wherein X is CH or N, and Z is O or N-R5, in which R5 is hydrogen or lower alkyl, R2 is hydroxy or lower alkoxy, R3 is hydrogen or lower alkyl which may have suitable substituent(s), R4 is ar(lower)alkyl which may have suitable substituent(s), A is carbonyl or sulfonyl, and Y is a bond or lower alkenylene, and pharmaceutically acceptable salt thereof. The disclosed compounds are useful for treating respiratory diseases such as bronchaedema. |