abstract |
A method of lowering serum cholesterol levels comprising administering to a patient a serum cholesterol lowering amount of a compound having the formula <IMAGE> (I) wherein n is 0, 1 or 2; R is hydroxyl, methoxy, C1-C7 alkanoyloxy, C3-C7 cycloalkanoyloxy, (C1-C6 alkoxy)-C1-C7 alkanoyloxy, substituted or unsubstituted aroyloxy, or substituted or unsubstituted aryloxycarbonyloxy; R1 is hydrogen, hydroxyl, chloro, bromo, methoxy, C1-C7 alkanoyloxy, C3-C7 cycloalkanoyloxy, (C1-C6 alkoxy)-C1-C7 alkanoyloxy, substituted or unsubstituted aroyloxy, or substituted or unsubstituted aryloxycarbonyloxy; R2 is a heterocyclic ring selected from the group consisting of pyrrolidino, piperidino, or hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof. |