| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-815 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9466
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D313-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D313-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D267-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-535 |
| filingDate |
1994-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13bb8fefafeb18db95d39594c373375e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13e6f90195bc3cbd66cb87d9f1c63927
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00cd4ebec77b8c3a447151aeb565a71f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87d20f0352cdd579535fabf3e28ae0f7 |
| publicationDate |
1995-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5464767-A |
| titleOfInvention |
Reagents and methods for the quantification of total doxepins in biological fluids |
| abstract |
Immunoassay methods and reagents for the quantification of total doxepins (i.e., E-doxepin, Z-doxepin, E-desmethyldoxepin, and Z-desmethyldoxepin) in a test sample are disclosed. The quantification of total doxepins is accomplished in an immunoassay employing antibodies and labeled reagents prepared with doxepin derivatives of the Formula II: ##STR1## wherein Y-Z can be C=CH or N-CH 2 , R 1 is a linking group, R 2 can be H or CH 3 , and Q can be a detectable moiety or an immunogenic carrier material. The antibody reagent comprises antibodies which are capable of binding to total doxepins and which are produced with one or more immunogens prepared from the doxepin derivative of Formula II, and the labeled reagent is also prepared from the doxepin derivative of Formula II. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5804395-A |
| priorityDate |
1991-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |