| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbd35d80213ac1a882630c19c99f22be |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-04 |
| filingDate |
1987-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88b681a800c54b9fcfd9020b7183e006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_323504ad429ae5b0546f721bfc2d50cb |
| publicationDate |
1995-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5441878-A |
| titleOfInvention |
Preparation of uniform droplets by using gas pressure to force liquid from a syringe and flowing gas to detach droplets |
| abstract |
An apparatus and method for the formation of droplets of uniform size on a laboratory scale are described. A syringe having a plunger and a needle with an orifice at the tip corresponding to a 12-30 gauge needle is inserted into a block member having a cavity such that the needle of the syringe extends through an opening in the bottom of the block member. The block member has a gas inlet into a side of the cavity for flowing of gas pass the orifice of the needle. The block member is mounted in a support housing such that the syringe is in a vertical position. To form droplets, pressure is applied to the plunger, preferably by a piston under gas pressure, to force liquid from the needle tip orifice to form droplets and flowing gas pass the tip to detach droplets of a desired size. In a preferred embodiment, the liquid is a suspension containing living cells and alginate, and droplets formed are solidified in a solidifying medium such as a calcium chloride solution to obtain microcapsules containing living cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9962607-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2006295114-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007071732-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0062932-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0062932-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6461572-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6391149-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5660630-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015075300-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6780507-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8518394-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9739327-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005032199-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6048562-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9625427-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109258633-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6620620-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018299476-A1 |
| priorityDate |
1987-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |