http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5440030-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_046e16bd6918ef3cd62184605b15a413 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J27-128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-12 |
| filingDate | 1993-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1995-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf89e2bf52677b18b9f03e8139a4f199 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d1d34da34f8291c3ac2f4fcf465bbd2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f416f01b55dc7c58483021b023f5ab7b |
| publicationDate | 1995-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5440030-A |
| titleOfInvention | Ru catalyzed acyloxylation process for preparing 4-acyloxyazetidinone derivatives |
| abstract | A process for preparing a 4-acyloxyazetidinone or a derivative thereof represented by formula (IV): n atom, a lower alkyl group, a hydroxyethyl group, or a protected hydroxyethyl group; R3 represents an alkyl group having from 1 to 10 carbon atoms which may be substituted with a halogen atom, a cyano group, a lower alkoxy group or a phenyl group, or a substituted or unsubstituted phenyl group, provided that the alpha -positioned carbon atom of said alkyl group should not have more than two halogen atoms; and R4 represents a hydrogen atom, a lower alkyl group, or a lower alkoxycarbonyl group, which is useful as an intermediate for penera antibiotics is disclosed, comprising reacting azetidinone or a derivative thereof represented by formula (II): <IMAGE> (II) wherein R1 is as defined above, and R2 represents a hydrogen atom, a lower alkyl group, a lower alkoxycarbonyl group, or a carboxyl group, with a carboxylic acid represented by formula (III): R3COOH(III) wherein R3 is as defined above, in the presence of (1) a transition metal compound selected from a ruthenium compound, an osmium compound, and a cobalt compound, (2) an aldehyde having 2 or more carbon atoms, provided that the carbon atom at the alpha -position thereof should not have two or more halogen atoms, and (3) oxygen. The compound (IV) can be prepared with safety through simple and easy operations. |
| priorityDate | 1991-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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