| abstract |
A compound having the formula ##STR1## wherein R 4 and R 5 independently are hydrogen, halogen, CF 3 , CN, NO 2 or SO 2 NR 1 R 2 wherein n R 1 is hydrogen or C 1-6 -alkyl which may be straight, branched or cyclic, n R 2 is hydrogen or C 1-6 -alkyl which may be straight, branched or cyclic, or wherein R 1 and R 2 together represent --(CH 2 ) n --A--(CH 2 ) m --, wherein A is O, S, CH 2 or NR I , wherein R I is H, C 1-6 -alkyl which may be straight, branched or cyclic, n is 0, 1, 2, 3, 4, 5 and m is 0, 1, 2, 3, 4, 5; n R II is hydrogen, benzyl, (C═O)CF 3 , C 1-6 -carboxylic acid acyl, C 1-6 -alkoxy which may be branched or cyclic, or C 1-6 -alkyl which may be straight, branched or cyclic, CH 2 CO 2 R VI wherein R VI is hydrogen or C 1-6 -alkyl which may be straight or branched; n and a method of treating disorders of a mammal, including a human, responsive to the blockade of glutamic and aspartic acid receptors, with the same. |