| abstract |
A method of optimizing photodynamic therapy in which retained concentrations of photosensitizers administered are measured on a real time basis by percutaneous measurements of fluorescence. A light weight hand held fluorometer is used to percutaneously measure fluorescence emitted by photosensitizers in a tissue situs that is subject to photodynamic therapy. The use of real time determinations of the concentration of photosensitizers allow optimization of illumination intensity and duration. |