| abstract |
Pharmaceutical compounds of the formula: <IMAGE> (I) <IMAGE> <IMAGE> R1 to R8 are each hydrogen or C1-4 alkyl, m, n and p are each 0, 1, or 2, q is 0, 1, 2 or 3, X and Z are each C1-4 alkyl, C1-4 alkoxy, hydroxy, nitro, cyano, halo, trihalomethyl, carboxy, C1-4 alkoxy-carbonyl or phenyl, and in addition z, together with the phenyl ring to which it is attached, can be: <IMAGE> Y is -O-, -S- or -CH2-, V is -(CH2)r- or -(CH2)rS- where r is 1 to 15, and W is hydrogen or optionally substituted phenyl; and salts thereof. |