Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6459 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0028 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-72 |
filingDate |
1993-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1995-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e35e8ea3d0cfe09e50770929cfc1e9be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28ab13e0bff722d5e870258bc1f675f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_819cf4966e158678bdf591c5da7d0959 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_521bb7541299db99ef0059932d0cf12a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5b47a6c0d1eacc46fe9ad49ba024fd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5db0ae346110b2f920ab531d5d4d41f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5d197bd8d2ba1bcd94b1395bac4bb96 |
publicationDate |
1995-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5424198-A |
titleOfInvention |
Human tPA production using vectors coding for DHFR protein |
abstract |
A method for producing tissue plasminogen activator (t-PA)in eukaroytic host cells is disclosed. Enhanced levels of t-PA production are obtained by co-amplification of the t-PA gene through treatment of cultures transformed with mutant or wild-type DHFR with methotrexate. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004191239-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6462067-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6730692-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6407133-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6242473-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003149090-A1 |
priorityDate |
1983-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |