| abstract |
Pharmaceutical compositions and a method for immunization of mammals against atherosclerosis including steps of a) obtaining blood from a mammal; b) isolating low density lipoprotein from the blood; c) fusing the lipoprotein in vitro to obtain heavy microemulsion lipoprotein fusion particles having new antigenic determinants; d) administering the fusion particles obtained in step (c) to a mammal; and e) allowing the immune system to clear fusion lipoprotein particles from the mammal. |