| abstract |
Hydrochloride salts of heterocyclic spiro compounds are provided and can be represented by the following general formula: ##STR1## wherein A represents piperidine or N alkyl piperidine or N alkylene attached to a non adjacent piperidine ring carbon, X is S or O, Y is carbonyl, thiocarbonyl, methylene, R 5 methylene, ##STR2## alk in which R 1 to R 3 ,R 6 ,R 7 are H or alkyl, R 4 is H, alkyl, COOH, or ester, or --C alkyl, R 5 is halo, OH,SH, O alkyl, S alkyl, O acyl or S acyl, and Z, and Z 2 are O or S. The above compounds act upon muscarinic acetylcholine receptors, thereby activating the acetylcholine nervous functions in the central nervous system. |