| abstract |
A compound having pharmaceutical activity, of the formula ##STR1## in which A is hydrogen or --(CR 1 R 2 ) x R 3 where x is 0 or 1 to 4, R 1 and R 2 are each hydrogen or C 1-4 alkyl and R 3 is --CN, --COOH, tetrazolyl or --CONHSO 2 R 4 where R 4 is optionally substituted phenyl, and ##STR2## where R 5 and R 6 are each hydrogen, C 1-4 alkyl or --(CR 1 R 2 ) x R 3 where x, R 1 , R 2 and R 3 are as defined above, and R 7 is hydrogen, C 1-4 alkyl or --(CR 1 R 2 ) x R 3 where x is 1 to 4, and R 1 , R 2 and R 3 are as defined above; n provided that when A is hydrogen at least one of R 5 , R 6 and R 7 n is --(CR 1 R 2 ) x R 3 , and provided that when ##STR3## A is --(CR 1 R 2 ) x R 3 and x is 1 to 4 then R 3 is --CONHSO 2 R 4 ; n and salts and esters thereof. |