| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e83d93ed02bbd6159e99b5a7796e3686 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-02 |
| filingDate |
1993-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ab91b736509bdb4ca2b7e7eb4d4b153
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_364d2c4214a726af0ed5d93321d6c557 |
| publicationDate |
1995-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5407828-A |
| titleOfInvention |
Process for stereoselection of (2R,3S)-3-phenylgycidic ester using lipase from candida antarctica |
| abstract |
The invention relates to the preparation of an optically active ester of trans-3-phenylglycidic acid in which a mixture of the 2 enantiomers of the trans-3-phenylglycidic acid ester is stereoselectively hydrolyzed using an enzyme originating from Candida antarctica and the non-hydrolyzed ester is separated off from the reaction mixture. A racemic mixture of trans-phenylglycidic acid esters is selectively and enzymatically hydrolyzed in a relatively short reaction time, the residual ester being obtained in a high yield and with a high e.e. Such esters are used for the preparation of pharmaceuticals such as benzothiazepines and benzazepines. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6277626-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107446960-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5604120-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6638758-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5571704-A |
| priorityDate |
1992-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |