| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b4beef0c137d9094e6918ee382be22f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-808
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-829 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54313
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54333 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 |
| filingDate |
1994-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3daf4b8d5d2d3dac8275fbf5101ab656
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_244a488cadd899afebd2351b0617916f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15a68d109e4f57906934363691aca0ef |
| publicationDate |
1995-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5405743-A |
| titleOfInvention |
Reversible agglutination mediators |
| abstract |
Compounds and methods are disclosed for reversibly aggregating particles suspended in a liquid medium. The method comprises combining the liquid medium containing the particles with a polyionic polymer capable of aggregating the particles under conditions suitable for such aggregation. Thereafter, the particles are contacted with a chemical reagent capable of cleaving the polyionic polymer under conditions sufficient to reverse the aggregation. Optionally, magnetic particles are added to the liquid medium in the present method under conditions for non-specific binding and the medium including the aggregates is subjected to a magnetic field gradient to separate the aggregates from the medium. The compounds of the present invention are polyions. The aggregation of the particles is reversible upon contact with chemical agents which cleave at least some of the bonds within the polyionic polymer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5985658-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003203507-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6451616-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6689615-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008202933-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8263022-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6620627-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8968678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6623982-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005155910-A1 |
| priorityDate |
1987-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |