| abstract |
Pharmaceutical compounds of the formula: <IMAGE>alkoxy, halogen or nitro, and n is 0, 1, 2 or 3, R2 is hydrogen, C1-4 alkyl or C2-4 alkenyl, R3 is hydrogen, C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, halogen, nitro or -NR'R'' where R' and R'' are each hydrogen or C1-4 alkyl, R4 and R5 are each hydrogen, C1-4 alkyl, optionally substituted phenyl or C6-9 cycloalkyl optionally substituted by 1 to 4 C1-4 alkyl groups, R6 is optionally substituted phenyl, tetrahydronaphthyl, phthalimido, saccharinyl, glutaramido, C6-10 cycloalkyl optionally substituted with 1 to 4 C1-4 alkyl groups or a phenyl group, or C4-9 heterosubstituted cycloalkyl optionally substituted with 1-4 alkyl groups, x is 1, 2 or 3, y is 0 or 1 and z is 0, 1, 2 or 3; and salts thereof. |