| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36e8050eec40967e1cbc39ff89f2607d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-416
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-18 |
| filingDate |
1994-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd540897b9aed433caf2bf702aaf4dd2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24591c2d8b1c2eadd8e1f2606357ab17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68db3fe1c1db90046cd03a5227922de1 |
| publicationDate |
1995-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5387515-A |
| titleOfInvention |
Process for providing a 6-ketone from morphine or an ether derivative thereof using morphine dehydrogenase |
| abstract |
Two enzymes, one an acetylmorphine carboxyesterase (AMCE), the other a morphine dehydrogenase (MDH), have been isolated from bacteria. The AMCE degrades heroin to morphine and the MDH oxidizes morphine to morphinone, with the aid of a cofactor. More particularly, the invention pertains to a process for preparing a 6-ketone from morphine or a methyl or ethyl derivative thereof. The process comprises oxidizing morphine or an ether derivative in the presence of a morphine dehydrogenase and the cofactor NADP+. These reactions are used in detection of heroin (using the two reactions coupled together) or morphine. The enzymes can be incorporated in sensors for this purpose. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-758153-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6225074-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5571685-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0057166-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10429400-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6720164-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015171839-A1 |
| priorityDate |
1989-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |