| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a333e6344b62fb21a7c1ee592b165fca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36a0771cc6e5b18dd95625919ede6534 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-92 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-045 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90 |
| filingDate |
1993-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1995-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_087fd7e803c1ceda9afe481bf4085c29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e80f67f49f9e49c028c1c9bb7c418d2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33f768dca767bcc8e26b68edec708029
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_218a935c37caeccc0e01b944d7cc48d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49a5df0f756de810f2e4195a4e5016dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cccee5a6241c6c058cbefa3630fc28a8 |
| publicationDate |
1995-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5384257-A |
| titleOfInvention |
Glucose isomerases with an altered pH optimum |
| abstract |
A method for selecting amino acid residues is disclosed which upon replacement will give rise to an enzyme with an altered pH optimum. The method is specific for metalloenzymes which are inactivated at low pH due to the dissociation of the metal ions. The method is based on altering the pKa of the metal coordinating ligands or altering the Kass for the metal binding. New glucose isomerases with an altered pH optimum are provided according to this method. These altered properties enable starch degradation to be performed at lower pH values. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018202880-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5989887-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008113415-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8012713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010297696-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919300-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5863783-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11066659-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11674129-B2 |
| priorityDate |
1990-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |