| abstract |
The invention provides compounds of the general formula (I) <IMAGE> (I) and physiologically acceptable salts, solvates or non-toxic metabolically labile esters thereof where R1 represents a halogen atom; Ar represents the group <IMAGE> R3 represents a C-linked tetrazolyl group; R4 and R5, which may be the same or different, each independently represent a hydrogen atom or a halogen atom or a C1-6 alkyl group; and Het represents an N-linked imidazolyl group optionally substituted at the 2-position. The compounds may be used in the treatment or prophylaxis of hypertension and diseases associated with cognitive disorders. |