abstract |
Compounds corresponding to the formula (I) ##STR1## in which X represents dibromomethyl, formyl, (C 1-4 )alkyl, or a group CH(OR 5 ) 2 or CH(OH)OR 5 , wherein the or each R 5 is hydrogen (C 1-3 )alkyl or the two R 5 's in the case of CH(OR 5 ) 2 are linked to provide a 1,3-dioxolane or 1,3-dioxane ring, and Y represents hydrogen, 1,1-dimethylethyl, triphenylmethyl, trimethylstannyl, tributylstannyl, (1,1-dimethylethyl)dimethylsilyl, (1,1-dimethylethyl)diphenylsilyl, 2-cyanoethyl, or a group CH 2 OR 6 wherein R 6 is methyl, phenylmethyl, 1,1-dimethylethyl, 2,2,2-trichloroethyl, benzyloxycarbonyl or 2,2,2-trichloroethyloxycarbonyl, Y being in position 1 or 2 on the tetrazole ring. The compounds of formula (I) are useful as intermediates in the synthesis of compounds possessing therapeutic activity. |