abstract |
The present invention provides compounds of the formula <IMAGE> wherein R is hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C6 cycloalkyl, or C1-C6 haloalkyl; A and A' are independently hydrogen, C1-C6 alkyl, nitro, amino, a 5-6 membered organic heterocycle containing 1, 2, or 3 hetero atoms selected from nitrogen or sulfur, C1-C6 alkoxy, or phenyl; or A and A' taken together form a group of the formulae <IMAGE> <IMAGE> wherein X is hydrogen, halo, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkoxycarbonyl, amino, nitro, or carboxy; and Y is nitrogen or carbon; or a pharmaceutically acceptable salt thereof; pharmaceutical compositions and methods of treatment using the above compounds. |