http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5349086-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12ebbccf13fdf78bd50c9633c103d352 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-04 |
| filingDate | 1992-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d66d543aecbb78f3bc4a65e402830d6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e55d7f5bb140ea8f6590199fca824ad |
| publicationDate | 1994-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5349086-A |
| titleOfInvention | Method for the preparation of 4-phenyl-1,3-benzodiazepins and precursors thereof |
| abstract | A compound of the formula ##STR1## is prepared by reacting an N-acylated-o-toluidine of the formula ##STR2## with n-alkyllithium to form a dilithio intermediate of the formula ##STR3## which can then be quenched with N-benzylidenemethylamine to form compound II. Hydrolysis of compound(II) yields the free base ##STR4## or its salt, which can be cyclized to form 4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine or its physiologically acceptable salts, which are useful as pharmacological agents. |
| priorityDate | 1981-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 79.