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filingDate 1992-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1994-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5349055-A
titleOfInvention Nerve growth factor having altered receptor binding specificities
abstract A method of altering the receptor binding properties and the stability of neurotrophic factors is set forth. Mutant neurotrophic factors having altered receptor binding specificities are described. Specific embodiments include neurotrophic factors that bind trk receptors but do not bind to the low affinity NGF receptor.
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