| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b9f373878f16dc291ff597162e9b344 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-503 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 |
| filingDate |
1991-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1994-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfff3052a1141a8a20f085ca1de7b5f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2971748aa86ea2674f9a3b0128adb998
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80a0689df6435098db1c4d0bc3a9f858
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_410d2db1707891b00bd843dabd352ac0 |
| publicationDate |
1994-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5348863-A |
| titleOfInvention |
Process for the enzymatic preparation of basic fibroblast growth factor |
| abstract |
PCT No. PCT/EP91/01428 Sec. 371 Date Apr. 2, 1992 Sec. 102(e) Date Apr. 2, 1992 PCT Filed Jul. 30, 1991 PCT Pub. No. WO92/02539 PCT Pub. Date Feb. 20, 1992.A bFGF is prepared by: (i) forming an adduct between heparin or heparan sulphate and a bFGF which has the 9-10 Leu-Pro bond; (ii) treating the adduct with pepsin A or cathepsin D, thereby cleaving the said bond; and (iii) releasing from the adduct the bFGF thus obtained. This process may be applied to prepare the 146 amino acid form of bFGF from longer forms of bFGF. It may also be used to produce a single form of bFGF from a mixture of bFGFs whose amino acid sequences differ only by having different N-terminii. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6737404-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6274712-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005159350-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6767722-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7138374-B2 |
| priorityDate |
1990-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |