http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5346914-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-12 |
| filingDate | 1993-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6cd22a45e951f372bf7ed3738e402e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bd58976737bf44ce69e04064d7e73b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4d1f5bcc757f907b5187c3eefbde357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bc4f8cd8fcb41bd1f3e2138eda2a719 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d284aa430b8d9b648ee20b5b37bec90 |
| publicationDate | 1994-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5346914-A |
| titleOfInvention | (4-alkoxypyran-4-yl) substituted arylalkylaryl-, arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase |
| abstract | Compounds of the structure <IMAGE> wherein W is selected from <IMAGE> where Q is oxygen or sulfur, R6 and R7 are hydrogen or alkyl, or R6 and R7, together with the nitrogen atoms to which they are attached, define a radical of formula <IMAGE> R8 is selected from hydrogen, alkyl, haloalkyl, optionally substituted phenyl, hydroxyalkyl, aminoalkyl, carboxyalkyl, (alkoxycarbonyl)alkyl, and (alkylaminocarbonyl)alkyl; Z is -CH2-, oxygen, sulfur, or -NR9 where R9 is hydrogen or alkyl, L1 and L2 are selected from a valence bond, alkylene, propenylene, and propynylene, R1, R2, R3, and R4 are independently selected from alkyl, haloalkyl, halogen, cyano, amino, alkoxycarbonyl, and dialkylaminocarbonyl, Y is selected from oxygen, -NR10, where R10 is hydrogen or alkyl, and <IMAGE> where n=0, 1, or 2, and R5 is alkyl, inhibit the biosynthesis of leukotrienes. These compounds are useful in the treatment or amelioration of allergic and inflammatory disease states. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5432194-A |
| priorityDate | 1993-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 504.