| abstract |
Oxyalkyne compounds corresponding to the formula Ia- or para-position is <IMAGE> R1 represents CH3 or NH2, R2 represents H or CH3, R3 represents H, C1-3-alkyl or COCH3, and Ar represents an aromatic residue selected from the group <IMAGE> <IMAGE> with the proviso that the substituents R4, R5 and R6 are the same or different and each substituent represents H, F, Cl, Br, C1-6-alkyl, CF3 or C1-6-alkoxy, and R7 represents H, F, Cl, Br, C1-3-alkyl or CF3, in the form of their racemates or mixtures of diastereoisomers or in optically active form, which are suitable active ingredients in pharmaceutical compositions. |