Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-48 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-06 |
filingDate |
1992-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1994-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67bb2dddd20d2a7758667911469a192a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc629b2287551ad28f725117cfce7ec3 |
publicationDate |
1994-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5318989-A |
titleOfInvention |
Cytotoxic bicyclo [7.3.1.]tridec-4-ene-2,6-diyne compounds and process for the preparation thereof |
abstract |
The present invention relates to a novel and efficient process for the preparation of 8-hydroxybicyclo[7.3.1]tridec-4-ene-2,6-diyne ring system which is part of the aglycone of esperemicin and to novel cytotoxic antitumor agents having said bicyclic ring system. The present invention also provides a method for treating mammalian malignant tumors by administering to an animal in need of such treatment an antitumor effective amount of a compound of the present invention. |
priorityDate |
1990-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |