Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b09f893b262cefd50c5e76c4b85d1c0a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-58 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44 |
filingDate |
1993-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1994-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab471fdb35456eb7711519bbb89ee41c |
publicationDate |
1994-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5310952-A |
titleOfInvention |
Method for the preparation of 6-hydroxy-2,5,7,8-tetraalkyl-2-(4-aminophenoxymethyl) chromans |
abstract |
A novel process for the preparation of aminochromans of the general formula: ##STR1## wherein R is a C 1 -C 4 alkyl group. In the process, a nitrochromanone of the general formula: ##STR2## is hydrogenated with hydrogen in the presence of a hydrogenation catalyst. The resultant aminochromanone (III) is reduced using zirconium oxide/isopropanol to the aminochromene (IV). The latter is finally hydrogenated with hydrogen in the presence of a hydrogenation catalyst to give the final product. The aminochromans are useful intermediates for the preparation of hypolipidaemic pharmaceuticals. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7608395-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5457124-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007059717-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009227603-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093253-B2 |
priorityDate |
1992-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |