| abstract |
PCT No. PCT/GB91/00710 Sec. 371 Date Oct. 27, 1992 Sec. 102(e) Date Oct. 27, 1992 PCT Filed May 3, 1991 PCT Pub. No. WO91/16898 PCT Pub. Date Nov. 14, 1991.Compounds of the general formula (7): (* CHEMICAL STRUCTURE *) (7) wherein X is a hydrogen atom or a hydroxyl group, Y is a hydrogen atom or a hydroxyl group and at least one of X and Y is a hydroxyl group and Z is a hydroxyl group or a methylol (-CH2OH) group, have anti-fungal activity, especially against organisms selected from Candida spp. and the athlete's foot/ringworm organisms Trichophyton mentagrophytes and Microsporum audonii. Compounds in which Z is a methylol (-CH2OH) group are claimed per se. |