| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a6a9431aa1fe5109ca95ad4e332231b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-4007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-4035 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-44717
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01T1-2942
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-4057
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-4258
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-482
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01T1-161 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-447
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B6-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01T1-29 |
| filingDate |
1991-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1994-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9c303065499ccbfd0cae511cfaff847
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_030addf3af5db4c51b93289818801fea |
| publicationDate |
1994-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5301671-A |
| titleOfInvention |
Two- and three-dimensional autoradiographic imaging utilizing charge coupled devices |
| abstract |
A two- and three-dimensional autoradiographical imaging system is provided which includes a charge coupled device for detecting the emission of radioactively labeled substances from materials such as tissue samples, brains of humans or animals, or substances used in electrophoresis applications. In a first aspect, a radioactively labeled substance is included in a tissue sample. The tissue sample is sequentially imaged by a charge coupled device and a sectioning tool such as a microtome to produce a plurality of two-dimensional images. A three-dimensional image of the tissue sample is generated by further processing of the plurality of two-dimensional images derived from the charge coupled device. In a further aspect of the invention, a charge coupled device is utilized to provide realtime imaging of metabolic or physiological parameters involved in brain activity. A charge coupled device is positioned adjacent a portion of brain tissue desired to be examined, the brain tissue having a radioactively labeled substance therein for detection by the charge coupled device. A two-dimensional realtime image is produced using the charge coupled device for use in clinical or behavioral studies. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007053057-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8324589-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009114830-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5520182-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9000386-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7737410-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9711325-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006169905-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8640585-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7391028-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5495111-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5877803-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10278656-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1029234-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11428832-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6330348-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014312226-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8563937-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1029234-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8158950-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007224699-A1 |
| priorityDate |
1991-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |