http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5292918-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7f82940e47ba7a1188f8e2ffca55e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-25 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C253-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-42 |
| filingDate | 1991-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1994-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a3d3af910f427a04ddf1849e269b219 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df6c260378617cd112ac595d425a91d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc3d412d07005ac0b24d555c423306ad |
| publicationDate | 1994-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5292918-A |
| titleOfInvention | Diastereoselective process for preparing n-substituted amino acids and derivatives |
| abstract | A process for preparing an (S,S) or (R,R) diastereoisomer of the formula: ##STR1## or salts, esters or amides thereof, wherein R 3 and R 4 independently represent hydrogen, alkyl, aryl or aryl substituted with halogen, alkyl, nitro or alkoxy, and n and m independently represent integers from one to six, comprising combining a cyanide compound of the formula: n n M.sup.1 C.tbd.N (III) n n wherein M 1 is hydrogen, trimethylsilyl or a metal, with an optional proton source, a solvent and a Lewis acid of the formula: n n M.sup.2 X.sub.4, AlCl.sub.3 or BF.sub.3 (IV) n n wherein M 2 is Sn or Ti and X represents chloro, bromo, fluoro or iodo, with an α-amino acid compound or salts or esters thereof, followed by addition of an acyl or acetal compound to give the diastereoisomer of formula (X). |
| priorityDate | 1990-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 157.